PXD066138

PXD066138 is an original dataset announced via ProteomeXchange.

Title	Proteomic Comparison Between Cell Supernatants of HPV-positive Epithelial Cells Treated by 37℃ and 44℃ Incubation
Description	Hyperthermia treatment (44℃incubation) demonstrates advantages of low recurrence rate and high efficacy in treating viral warts. This study aimed to investigate the exact modulatory mechanism of hyperthermia treatment on immune response. We performed 4D-FastDIA quantitative proteomics to analyze differential protein expression and secretory profiles in HPV-positive epithelial cells following 37°C or 44°C incubation, to compare the changes before and after hyperthermia treatment. Two HPV-positive cell lines were included in this dataset, the group A1 and A2 were CaSki cells treated by 37℃- or 44℃-incubation separately; the group A3 and A4 were SiHa cells treated by 37℃- or 44℃-incubation separately.
HostingRepository	iProX
AnnounceDate	2025-07-15
AnnouncementXML	Submission_2025-07-15_00:53:29.724.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ruiqun Qi
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-07-15 00:53:11	ID requested
⏵ 1	2025-07-15 00:53:30	announced

Dataset with its publication pending

submitter keyword: HPV-positive epithelial cells, supernatants, 4D-FastDIA quantitative proteomics analysis

Ruiqun Qi
contact affiliation	Department of Dermatology, the First Hospital of China Medical University
contact email	xiaoqiliumin@163.com
lab head
Ruiqun Qi
contact affiliation	Department of Dermatology, the First Hospital of China Medical University
contact email	xiaoqiliumin@163.com
dataset submitter

iProX dataset URI