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PXD066047

PXD066047 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleORF1p partners in dopaminergic neurons
DescriptionWe and others have previously observed a widespread expression of ORF1p in mouse and human neurons at steady-state. This somewhat surprising presence of ORF1p in neurons evokes the question of a possible physiological role of ORF1p specific to these cells. To address this question, we used a quantitative mass spectrometry approach to identify protein partners of endogenous ORF1p in mouse (differentiated MN9D) and human (differentiated LUHMES) dopaminergic neurons using well characterized and specific antibodies to ORF1p.
HostingRepositoryPRIDE
AnnounceDate2026-07-23
AnnouncementXMLSubmission_2026-07-23_00:46:32.065.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterVanessa Masson
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-07-11 01:23:29ID requested
12026-07-23 00:46:32announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: LINE-1, dopaminergic neurons,ORF1p
Contact List
Damarys Loew
contact affiliationHead of the Curie Institute Mass Spectrometry Platform
contact emaildamarys.loew@curie.fr
lab head
Vanessa Masson
contact affiliationInstitut Curie - Centre de Recherche
contact emailvanessa.masson@curie.fr
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD066047
PRIDE project URI
Repository Record List
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