PXD065925

PXD065925 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	HDAC3 mediates retinal endothelial cell metabolic reprogramming and angiogenesis
Description	Quantitative data-independent acquisition (DIA) analysis of effects of RGFP treatment in bovine retinal epithelial cells subjected to oxygen/glucose deprivation and reperfusion; 4 experimental groups (Normoxia_DMSO; Normoxia_RGFP; OGDR_DMSO; OGDR_RGFP) with 5 replicates of each.
HostingRepository	PRIDE
AnnounceDate	2025-10-07
AnnouncementXML	Submission_2025-10-06_18:32:19.445.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD065925
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Christian Mitchell
SpeciesList	scientific name: Bos taurus (Bovine); NCBI TaxID: NEWT:9913;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Astral

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-07-08 19:40:16	ID requested
⏵ 1	2025-10-06 18:32:20	announced

Publication List

10.1038/s41401-025-01642-3;
10.6019/PXD065925;
Mitchell CD, Morris CA, Wild M, Cunningham A, Chuesiang P, Mohammed AA, Nagalo BM, Rusch NJ, Fouda AY, Shosha E, HDAC3 mediates retinal endothelial cell metabolic reprogramming and angiogenesis. Acta Pharmacol Sin, ():(2025) [pubmed]

10.1038/s41401-025-01642-3;

10.6019/PXD065925;

Mitchell CD, Morris CA, Wild M, Cunningham A, Chuesiang P, Mohammed AA, Nagalo BM, Rusch NJ, Fouda AY, Shosha E, HDAC3 mediates retinal endothelial cell metabolic reprogramming and angiogenesis. Acta Pharmacol Sin, ():(2025) [pubmed]

Keyword List

submitter keyword: HK2,Retinopathy, proteomic analysis, mitochondrial fission, HDAC3, angiogenesis, endothelial cells, oxygen-glucose deprivation, glycolysis

submitter keyword: HK2,Retinopathy, proteomic analysis, mitochondrial fission, HDAC3, angiogenesis, endothelial cells, oxygen-glucose deprivation, glycolysis

Contact List

Abdelrahman Fouda
contact affiliation	College of Medicine University of Arkansas for Medical Science
contact email	AFouda@uams.edu
lab head
Christian Mitchell
contact affiliation	University of Arkansas for Medical Sciences
contact email	cdmitchell@uams.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD065925
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD065925

PRIDE project URI

Repository Record List

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