PXD065899

PXD065899 is an original dataset announced via ProteomeXchange.

Title	Secretome profiling of Onygena corvina on keratin-rich substrates
Description	Keratin-rich byproducts from the poultry, textile, and leather industries pose a significant challenge for sustainable waste management due to their highly recalcitrant nature. While microbial degradation may offer a viable solution, the mechanisms underlying keratin breakdown remain largely unexplored. In this study, we employed a high-resolution proteogenomic approach to characterize the keratinolytic machinery of Onygena corvina, a non-pathogenic saprophytic fungus. Using a membrane agar plate method with insoluble substrates, we obtained secretomes enriched in secreted and substrate-bound proteins during growth on α- and β-keratin-rich substrates, specifically wool and feather meal, as well as on casein (as control) at days 1, 2, and 3.
HostingRepository	PRIDE
AnnounceDate	2025-11-26
AnnouncementXML	Submission_2025-11-26_08:19:59.047.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Arturo Vera Ponce de Leon
SpeciesList	scientific name: Onygena corvina; NCBI TaxID: NEWT:180788;
ModificationList	acetylated residue; 2-pyrrolidone-5-carboxylic acid (Gln); monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-07-08 05:32:30	ID requested
⏵ 1	2025-11-26 08:19:59	announced

Dataset with its publication pending

submitter keyword: Onygena corvina, Bruker timsTOF, keratin degradation, secretome

Sabina Leanti La Rosa
contact affiliation	Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway
contact email	sabina.leantilarosa@nmbu.no
lab head
Arturo Vera Ponce de Leon
contact affiliation	Norwegian University of Life Sciences (NMBU)
contact email	arturo.vera.ponce.de.leon@nmbu.no
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD065899
     1. Label: PRIDE project
     2. Name: Secretome profiling of Onygena corvina on keratin-rich substrates