PXD065708

PXD065708 is an original dataset announced via ProteomeXchange.

Title	LC-MS-Based Quantitative Proteomic Profiling Reveals WWQ-03-012-Induced Alterations in Protein Expression of Human HEL Cells
Description	This experiment employs an analytical platform based on the Ultimate 3000 nano ultra-high-performance liquid chromatography system coupled to the Q Exactive Plus high-resolution mass spectrometer, combined with database search software, to conduct qualitative (or relative quantitative) analysis of proteins in samples from different experimental groups. The resulting protein list reflects the types and relative abundances of proteins detected in this mass spectrometry analysis.
HostingRepository	PRIDE
AnnounceDate	2026-02-09
AnnouncementXML	Submission_2026-02-08_16:29:47.794.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mei Husheng
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ

Revision	Datetime	Status	ChangeLog Entry
0	2025-07-02 20:36:12	ID requested
⏵ 1	2026-02-08 16:29:48	announced

10.1002/advs.202515127;

Mei H, Wen W, Zhang W, Zhang S, Sun T, Li G, Zhang J, Qi S, Zhou J, Li B, Zhao Y, Chen X, Li B, Xue Y, Lu W, Sun Y, Wang J, Shan H, Zhang S, Huang Y, Chen Y, Wang W, Liu Q, Lu W, Tan L, Ding Y, Fu J, Long J, Zhang L, Zhao B, Liang A, Jiang B, Yang J, Targeting DESI2 as a Novel Therapeutic Strategy for JAK2-Mutant Leukemias. Adv Sci (Weinh), 13(7):e15127(2026) [pubmed]

submitter keyword: JAK2-V617F，human cell，LC-MS

Jing Yang
contact affiliation	Department of Hematology, Tongji Hospital, Frontier Science Center for Stem Cell Research, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China
contact email	jingy@tongji.edu.cn
lab head
Mei Husheng
contact affiliation	Tongji university
contact email	hsmei@mail.ustc.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD065708

PRIDE project URI

• PRIDE
  1. PXD065708
     1. Label: PRIDE project
     2. Name: LC-MS-Based Quantitative Proteomic Profiling Reveals WWQ-03-012-Induced Alterations in Protein Expression of Human HEL Cells