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PXD065468

PXD065468 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic profiling of extracellular vesicles from virulent (vEV) and attenuated (aEV) Paracoccidioides brasiliensis isolate Pb18, as well as EVs released from virulent Pb18 exposed to oxidative (vEVOxi) and nitrosative (vEVNO) stress.
DescriptionThis dataset supports a comparative proteomic analysis of extracellular vesicles (EVs) and whole-cell extracts from the pathogenic fungus Paracoccidioides brasiliensis isolate Pb18. The study investigates protein cargo differences between EVs derived from virulent (vEV) and attenuated (aEV) variants, including vEVs exposed to oxidative (vEVOxi) and nitrosative (vEVNO) stress. Characterization of EVs included NTA, DLS, and Zeta potential measurements. Proteins were enzymatically digested and analyzed via nano-flow LC-MS/MS.
HostingRepositoryMassIVE
AnnounceDate2025-08-30
AnnouncementXMLSubmission_2025-08-30_12:05:35.229.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterCarla Elizabete Octaviano Azevedo
SpeciesList scientific name: Paracoccidioides brasiliensis;
ModificationListunknown modification; unknown modification
Instrumentinstrument model; instrument model
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-06-25 16:13:38ID requested
12025-08-30 12:05:35announced
Publication List
no publication
Keyword List
submitter keyword: Paracoccidioides brasiliensis, Extracellular vesicles, Nano LC-ESI-MS/MS, Oxidative stress, Nitrosative stress, Fungal pathogen, DatasetType:Proteomics
Contact List
Rosana Puccia
contact affiliationFederal University of Sao Paulo (UNIFESP)
contact emailrosana.puccia@unifesp.br
lab head
Carla Elizabete Octaviano Azevedo
contact affiliationEPM/UNIFESP
contact emailoctaviano.carla@unifesp.br
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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