PXD065433 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteogenomic investigation of plant constituents in herbal beverages |
| Description | Manufacturing adulteration is the major cause of discrepancies between the declared and actual composition of food products. The use of high-throughput sequencing of DNA barcodes is a promising method to identify adulterants, but is not yet widely used in practice. Food pre-processing and differences in GC composition can lead to unequal amplification or complete loss of DNA barcode components, so the results of genomic analysis require an independent confirmation method. Perhaps the most promising way to increase the accuracy of food ingredient identification is to use an orthogonal method based on very different physical principles than DNA sequencing, which involves the analysis of other plant cell components, to verify the results of HTS analysis. In this work, we decided to evaluate the suitability of a multi-omic approach, including coupled DNA barcode HTS analysis and proteomic analysis, to estimate food fraud in herbal beverages. To resolve disputed discordant results obtained during genomic and proteomic investigation of samples, we used traditional botanical morphology method. Among the samples studied, the combined approach revealed two adulterations of Epilobium with Lythrum, which could be dangerous for the unsuspecting consumer. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-30 |
| AnnouncementXML | Submission_2026-03-29_16:17:50.177.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Ivan Chudinov |
| SpeciesList | scientific name: food metagenome; NCBI TaxID: NEWT:870726; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-06-25 03:44:17 | ID requested | |
| ⏵ 1 | 2026-03-29 16:17:51 | announced | |
Publication List
| 10.1038/s41538-026-00747-1; |
| Chudinov IK, Krinitsina AA, Petukhova DA, Lukina-Gronskaya AV, Korneenko EV, Gremyacheva VD, Kovalenko AV, Fedorov OV, Kozhemyakin GL, Mironov KS, Antipin MI, Butenko IO, Logacheva MD, Speranskaya AS, Proteogenomic investigation of plant constituents in herbal beverages. NPJ Sci Food, 10(1):(2026) [pubmed] |
Keyword List
| submitter keyword: food quality control,Metabarcoding, proteomics, proteogenomics, food safety |
Contact List
| Ivan Chudinov |
|---|
| contact affiliation | Scientific Research Institute for Systems Biology and Medicine |
| contact email | ikchudinov@gmail.com |
| lab head | |
| Ivan Chudinov |
|---|
| contact affiliation | Scientific Research Institute for Systems Biology and Medicine |
| contact email | ikchudinov@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD065433
- Label: PRIDE project
- Name: Proteogenomic investigation of plant constituents in herbal beverages
