PXD065007 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Phase-Specific Antibiotic Resistance Mechanisms in an Escherichia coli B Strain |
| Description | In this study, we used liquid chromatography–tandem mass spectrometry to quantify protein abundance in the exponential and stationary phases of BLR (DE3) cells, an Escherichia coli B strain. Our findings are consistent with previous studies, which showed that metabolic processes such as translation and ribosome biogenesis decrease during the stationary phase compared to the fast-growing exponential phase, whereas tricarboxylic acid cycle activity increases. Importantly, our data reveal that distinct antibiotic resistance pathways are activated during the exponential and stationary phases, underscoring the potential for developing phase-specific antibiotic therapies. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-03 |
| AnnouncementXML | Submission_2026-09-03_13:12:17.281.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Tonya Zeczycki |
| SpeciesList | scientific name: Escherichia coli; NCBI TaxID: NEWT:562; scientific name: Bacteria; NCBI TaxID: NCBITaxon:2; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-06-13 10:54:10 | ID requested | |
| ⏵ 1 | 2026-09-03 13:12:17 | announced | |
Publication List
Keyword List
| submitter keyword: Stationary and exponetial phases. antibiotic resistance,E. Coli |
Contact List
| Eda Koculi |
|---|
| contact affiliation | Department of Chemistry and Biochemistry, The University of Texas at El Paso, El Paso, TX 79968, USA |
| contact email | ekoculi@utep.edu |
| lab head | |
| Tonya Zeczycki |
|---|
| contact affiliation | Brody School of Medicine at ECU |
| contact email | zeczyckit@ecu.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD065007
- Label: PRIDE project
- Name: Phase-Specific Antibiotic Resistance Mechanisms in an Escherichia coli B Strain
