PXD064953

PXD064953 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	IP-MS of SMARCC1-bound SWI/SNF complexes in PRT3789-treated Calu-6 and NCI-H1693 cell lines
Description	Immunoprecipitation-mass spectrometry (IP-MS) was performed in Calu-6 (SMARCA4-WT) and NCI-H1693 (SMARCA4-del) cell lines treated with the SMARCA2-selective degrader PRT3789 for 6 or 48 hours. SWI/SNF complexes were immunoprecipitated using an antibody against SMARCC1 and analyzed by LC-MS/MS.
HostingRepository	MassIVE
AnnounceDate	2025-08-04
AnnouncementXML	Submission_2025-08-04_14:25:07.867.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Michael Hulse
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	unknown modification
Instrument	instrument model

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-12 11:51:06	ID requested
⏵ 1	2025-08-04 14:25:08	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: IP-MS, SMARCC1, SWI/SNF complex, SMARCA2 degrader, PRT3789, Calu-6, NCI-H1693, NSCLC, proteomics, chromatin remodeling, TMT18, Orbitrap Fusion Lumos, DatasetType:Proteomics

submitter keyword: IP-MS, SMARCC1, SWI/SNF complex, SMARCA2 degrader, PRT3789, Calu-6, NCI-H1693, NSCLC, proteomics, chromatin remodeling, TMT18, Orbitrap Fusion Lumos, DatasetType:Proteomics

Contact List

Michael Hulse
contact affiliation	Prelude Therapeutics
contact email	mhulse@preludetx.com
lab head
Michael Hulse
contact affiliation	Prelude Therapeutics
contact email	mhulse@preludetx.com
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v10/MSV000098173/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v10/MSV000098173/