PXD064916

PXD064916 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Lysine acetylomic profiling of hybrid rice HY73 in response to drought
Description	This study investigates the molecular mechanisms underlying drought-resistant heterosis (DRH) in the elite hybrid rice HY73. Utilizing a quantitative lysine acetylome profiling approach on flag leaves of HY73 under well-watered (WW) and drought-stressed (DS) conditions, we aimed to unravel the role of protein lysine acetylation (Kac) in carbon metabolic reprogramming during drought adaptation. Critically, we identified phosphoglucomutase (OsPGM3) as a key metabolic switch whose K155 acetylation (K155ac) is dynamically downregulated under DS. This regulation orchestrates a strategic carbon reallocation, optimizing glucose-6-phosphate (G6P) flux towards lipid biosynthesis for stress resilience (MOS-AcCoA-FA/PR pathway) while maintaining efficient glucose-1-phosphate (G1P)-mediated sucrose export for yield potential. This dataset provides valuable insights into the sophisticated post-translational regulatory network that underpins superior DRH and yield stability in hybrid rice under water scarcity.
HostingRepository	PRIDE
AnnounceDate	2026-06-28
AnnouncementXML	Submission_2026-06-28_00:57:40.609.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wenbo Cheng
SpeciesList	scientific name: Oryza sativa (Rice); NCBI TaxID: NEWT:4530;
ModificationList	acetylated residue
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-11 23:03:52	ID requested
⏵ 1	2026-06-28 00:57:41	announced

Publication List

Ding W, Bi J, Chen S, Wu Z, Liao Z, Huang L, Luo L, Chen L, Zhang X, Integrated multi-omics analysis reveals carbon metabolic reprogramming as a mechanism of drought resistance in hybrid rice. Plant Commun, ():101936(2026) [pubmed]
10.1016/j.xplc.2026.101936;

Ding W, Bi J, Chen S, Wu Z, Liao Z, Huang L, Luo L, Chen L, Zhang X, Integrated multi-omics analysis reveals carbon metabolic reprogramming as a mechanism of drought resistance in hybrid rice. Plant Commun, ():101936(2026) [pubmed]

10.1016/j.xplc.2026.101936;

Keyword List

submitter keyword: Hybrid rice, Drought resistance, Lysine acetylation, Acetylome, Heterosis

submitter keyword: Hybrid rice, Drought resistance, Lysine acetylation, Acetylome, Heterosis

Contact List

Wei Ding
contact affiliation	State Key Laboratory of Genetic Engineering, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, 200438, China.
contact email	dingw21@m.fudan.edu.cn
lab head
Wenbo Cheng
contact affiliation	Shanghai Omicsspace Bioteh CO., LTD
contact email	wbcheng@omicsspace.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD064916
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD064916

PRIDE project URI

Repository Record List

[ + ]