PXD064834 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | RBM39 organizes an m⁶A-dependent silencing complex to degrade Tat mRNA and maintain HIV-1 latency |
| Description | Given the pivotal role of Tat in HIV-1 latency, we performed RNA pull-down assays in latently HIV-1-infected J-Lat 10.6 cells using biotinylated RNA probes (including a control RNA probe and a Tat-specific RNA probe) . Cell lysates were incubated with streptavidin agarose resin pre-bound to Tat RNA probes, and the enriched Tat RNA-binding proteins were separated by SDS-PAGE and analyzed by liquid chromatography mass spectrometry (LC-MS/MS) |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-10-31 |
| AnnouncementXML | Submission_2025-10-31_07:28:12.035.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | peiming huang |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-06-10 07:48:58 | ID requested | |
| ⏵ 1 | 2025-10-31 07:28:12 | announced | |
Publication List
Keyword List
| submitter keyword: LC/MS,Tat,RIP,j-lat 10.6 |
Contact List
| panting lab |
|---|
| contact affiliation | SUN YAT-SEN UNIVERSITY |
| contact email | pant8@mail.sysu.edu.cn |
| lab head | |
| peiming huang |
|---|
| contact affiliation | SUN YAT-SEN UNIVERSITY |
| contact email | huangpm6@mail2.sysu.edu.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD064834 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD064834
- Label: PRIDE project
- Name: RBM39 organizes an m⁶A-dependent silencing complex to degrade Tat mRNA and maintain HIV-1 latency
