PXD064823

PXD064823 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	proteomic quantitative analysis of cell supernatants from Ddx49f/f and Ddx49hep-/-
Description	In our study, we demonstrated that the supernatant components secreted by hepatocytes are capable of activating hepatic stellate cells and promoting their differentiation into myofibroblasts. To identify the secretome regulated by DDX49 in hepatocytes, primary liver cells isolated from both control and DDX49-knockout mice were subjected to OA/PA stimulation for 24 hours. Subsequently, the conditioned media were collected and subjected to 10X high-depth proteomic quantitative analysis.
HostingRepository	PRIDE
AnnounceDate	2026-01-09
AnnouncementXML	Submission_2026-01-09_08:29:43.166.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yunhui Li
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF HT

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-10 02:50:44	ID requested
⏵ 1	2026-01-09 08:29:43	announced

Publication List

10.1016/J.CMET.2025.12.015;

10.1016/J.CMET.2025.12.015;

Keyword List

submitter keyword: proteomic quantitative analysis, cell supernatants

submitter keyword: proteomic quantitative analysis, cell supernatants

Contact List

Yunhui Li
contact affiliation	National Key Laboratory of Immunity and Inflammation
contact email	liyunhuigirl@163.com
lab head
Yunhui Li
contact affiliation	National Key Laboratory of Immunity and Inflammation
contact email	liyunhuigirl@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD064823
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD064823

PRIDE project URI

Repository Record List

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