PXD064812
PXD064812 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | DDX39B K63-linked ubiquitination mediated by TRIM28 promotes NSCLC metastasis by enhancing ECAD lysosomal degradation |
| Description | DDX39B interacted with E3 ubiquitin ligase TRIM28 and underwent TRIM28-mediated K63-linked ubiquitination at Lys241, Lys384, and Lys398, leading to DDX39B protein stabilization and upregulation. |
| HostingRepository | iProX |
| AnnounceDate | 2025-06-10 |
| AnnouncementXML | Submission_2025-07-16_00:51:38.937.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Ping Lin |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | ubiquitination signature dipeptidyl lysine |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-06-10 00:53:19 | ID requested | |
| ⏵ 1 | 2025-07-16 00:51:40 | announced |
Publication List
| Yuan H, Li Q, Li L, Zhao G, Zhang J, Feng T, Guo Y, Kou Q, Li S, Li S, Zhao M, Wang G, Wang Q, Qu J, Yu H, Chen H, Liu L, Li K, Lin P, DDX39B K63-linked ubiquitination mediated by TRIM28 promotes NSCLC metastasis by enhancing ECAD lysosomal degradation. Signal Transduct Target Ther, 10(1):221(2025) [pubmed] |
Keyword List
| submitter keyword: DDX39B PTMs (ubiquitination, phosphorylation, etc.) |
Contact List
| Ping Lin | |
|---|---|
| contact affiliation | West China Hospital, Sichuan University |
| contact email | linping@scu.edu.cn |
| lab head | |
| Ping Lin | |
| contact affiliation | West China Hospital, Sichuan University |
| contact email | linping@scu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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