PXD064807

PXD064807 is an original dataset announced via ProteomeXchange.

Title	The potential binding proteins of FOXQ1 were detected by mass spectrometry technology, laying the foundation for the subsequent in-depth study of its molecular mechanism
Description	First, Flag-FOXQ1 was overexpressed in HCT-116 cells. Subsequently, the Flag-FOXQ1 complex was enriched via immunoprecipitation (IP) technology. The complex was then washed four times with phosphate-buffered saline (PBS), denatured in loading buffer by boiling, and separated via gel electrophoresis to obtain the protein components of the complex. Finally, mass spectrometry analysis was performed for identification.
HostingRepository	iProX
AnnounceDate	2025-06-09
AnnouncementXML	Submission_2025-08-05_21:54:52.727.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wendong Yang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-09 23:49:49	ID requested
1	2025-06-09 23:50:12	announced
⏵ 2	2025-08-05 21:54:53	announced	2025-08-06: Add info.

Yang WD, Zhang ZH, Zhao MY, Shao K, Ma YF, Shen Q, Lu MR, Shao ZY, Xu JY, Cao MH, Meng S, Chu SF, Yong HM, Ding J, Bai J, P300-dependent acetylation of the FOXQ1 complex activates super-enhancers to promote colorectal cancer proliferation and metastasis. Commun Biol, 8(1):1016(2025) [pubmed]

submitter keyword: FOXQ1, potential binding proteins

Jin Bai
contact affiliation	XuZhou Medical University
contact email	bj@xzhmu.edu.cn
lab head
Wendong Yang
contact affiliation	XuZhou Medical University
contact email	anywd@sina.com
dataset submitter

iProX dataset URI