PXD064735 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomics of functional and dysfunctional hybridomas |
| Description | Proteomics sequencing was utilized to investigate the key pathways and genes regulating hybridoma homeostasis and antibody production. Two phenotypes, including functional and dysfunctional hybridomas exhibiting and lacking binding specificity against chlorothalonil (a representative fungicide), were screened via limiting dilution and used for sequencing. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-06 |
| AnnouncementXML | Submission_2026-04-05_16:31:36.730.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Rubing Zou |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro 2 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
| 0 | 2025-06-06 21:46:22 | ID requested | |
| ⏵ 1 | 2026-04-05 16:31:37 | announced | |
Publication List
| Zou R, Lu X, Liu Y, Yang P, Sun S, Liu Y, Mo Y, Zhu G, Lee JS, Guo Y, Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR-Mediated Control of Immunoglobulin Homeostasis in Hybridomas. Adv Sci (Weinh), 13(17):e14140(2026) [pubmed] |
| 10.1002/advs.202514140; |
Keyword List
| ProteomeXchange project tag: Antibodies (B/D-HPP) |
| submitter keyword: antibody,Hybridoma |
Contact List
| Yirong Guo |
| contact affiliation | Institute of Pesticide and Environmental Toxicology, College of Argriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China. |
| contact email | yirongguo@zju.edu.cn |
| lab head | |
| Rubing Zou |
| contact affiliation | Insitute of Pesticide and Environmental Toxicology, Zhejiang University |
| contact email | zourubing@zju.edu.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD064735 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD064735
- Label: PRIDE project
- Name: Proteomics of functional and dysfunctional hybridomas