PXD064613 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Mouse brain endothelial cells LC-MS/MS |
| Description | In our study, we used immunofluorescence to examine brain endothelial cells (ECs) from Slc3a2 ECKO mice and found that blood-brain barrier markers, including tight junction proteins and transcytosis-associated proteins, exhibited significant changes compared to Slc3a2 WT mice. To further investigate these findings, we performed flow cytometry sorting on brain ECs from both Slc3a2 WT and ECKO mice. Subsequently, we conducted proteomic sequencing to identify additional molecular changes, particularly those related to blood-brain barrier markers. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-27 |
| AnnouncementXML | Submission_2026-03-27_08:30:45.357.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Shilun Yang |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-06-04 03:07:23 | ID requested | |
| ⏵ 1 | 2026-03-27 08:30:45 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Endothelial cells, Blood-brain barrier,Mouse, Brain, LC-MS/MS |
Contact List
| Junlei Chang |
|---|
| contact affiliation | Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Xueyuan Avenue 1068, Nanshan, Shenzhen, Guangdong, 518055, China. |
| contact email | jl.chang@siat.ac.cn |
| lab head | |
| Shilun Yang |
|---|
| contact affiliation | Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences |
| contact email | sl.yang@siat.ac.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD064613 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD064613
- Label: PRIDE project
- Name: Mouse brain endothelial cells LC-MS/MS
