PXD064548
PXD064548 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | RSK Inhibition Rewires Kinase Networks in Esophageal Cancer |
| Description | Our study reveals that RSK inhibition reprograms kinase networks to enforce stress adaptation, maintaining oncogenic homeostasis despite perturbations. These findings highlight a potential therapeutic window for early intervention strategies, suggesting that combination strategies may enhance the efficacy of RSK-directed therapies in ESCC. |
| HostingRepository | iProX |
| AnnounceDate | 2025-06-02 |
| AnnouncementXML | Submission_2025-06-03_01:16:47.380.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xi Chen |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-06-03 01:16:27 | ID requested | |
| ⏵ 1 | 2025-06-03 01:16:47 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: RSK inhibitor, ESCC, phosphoroteomics |
Contact List
| Xi Chen | |
|---|---|
| contact affiliation | Sichuan Provincial People’s Hospital |
| contact email | cxde515@uestc.edu.cn |
| lab head | |
| Xi Chen | |
| contact affiliation | Sichuan Provincial People’s Hospital |
| contact email | cxde515@uestc.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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