PXD064540

PXD064540 is an original dataset announced via ProteomeXchange.

Title	Therapeutic effect and underlying mechanism of cell therapy on cyclophosphamide-induced premature ovarian insufficiency mouse model
Description	An equivalent dosage of human umbilical cord-derived mesenchymal stem cell (HucMSC), adipose tissue-derived mesenchymal stem cell (ADSC), and SVF was orthotopically administered into a cyclophosphamide (CTX)-induced premature ovarian insufficiency (POI) mouse model. The therapeutic impacts were meticulously evaluated employing a suite of assays. The underlying mechanisms were investigated through RNA sequencing (RNA-seq) and mass spectrometry, offering insights into the cellular and molecular responses.
HostingRepository	iProX
AnnounceDate	2025-05-31
AnnouncementXML	Submission_2025-06-03_00:22:44.638.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yingyi Zhang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-03 00:22:21	ID requested
⏵ 1	2025-06-03 00:22:45	announced

Dataset with its publication pending

submitter keyword: mesenchymal stem cells, stromal vascular fraction, premature ovarian insufficiency, female fertility preservation, oxidative stress

Songying Zhang
contact affiliation	Sir Run Run Shaw Hospital (SRRSH), affiliated with Zhejiang University School of Medicine
contact email	zhangsongying@zju.edu.cn
lab head
Yingyi Zhang
contact affiliation	Sir Run Run Shaw Hospital (SRRSH), affiliated with Zhejiang University School of Medicine
contact email	zhangyingyi@zju.edu.cn
dataset submitter

iProX dataset URI