PXD064483

PXD064483 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Data in support of Proteomic study of diffuse large B-cell lymphoma identifies proteins associated to single drug components of R-CHOP
Description	Diffuse large B-cell lymphoma (DLBCL) is a molecularly and pathogenically heterogenous disease with varying clinical outcomes which is reflected in the substantial group of patients developing relapse/refractory disease (rrDLBCL) after standard treatment with the combinatory regimen R-CHOP. The molecular background of developing rrDLBCL is yet to be fully understood and prognostic and/or companion diagnostic biomarkers for identification, treatment stratification and prediction of adverse treatment effects of these patients are in high demand. Therefore, this exploratory study aims to use comprehensive proteomic relative quantitative data to identify proteins that are associated with treatment response. Proteome profiles of untreated DLBCL cells were analyzed by groupwise comparison between cell lines having poor and good response to rituximab, cyclophosphamide, doxorubicin and vincristine, respectively, determined by subsequent drug response screen.
HostingRepository	PRIDE
AnnounceDate	2025-12-08
AnnouncementXML	Submission_2025-12-07_21:34:16.159.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Allan Stensballe
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-01 00:24:43	ID requested
⏵ 1	2025-12-07 21:34:17	announced

Publication List

10.3390/biomedicines13112709;
Haraldsd, ó, ttir H, Br, ø, ndum RF, Enemark MH, Honor, é B, Ludvigsen M, Aboo C, Stensballe A, J, ø, rgensen JM, Due H, Dybk, æ, r K, Proteomic Study of Diffuse Large B-Cell Lymphoma Identifying Proteins Associated with R-CHOP Response. Biomedicines, 13(11):(2025) [pubmed]

10.3390/biomedicines13112709;

Haraldsd, ó, ttir H, Br, ø, ndum RF, Enemark MH, Honor, é B, Ludvigsen M, Aboo C, Stensballe A, J, ø, rgensen JM, Due H, Dybk, æ, r K, Proteomic Study of Diffuse Large B-Cell Lymphoma Identifying Proteins Associated with R-CHOP Response. Biomedicines, 13(11):(2025) [pubmed]

Keyword List

submitter keyword: rrDLBCL,R-CHO, DLBCL

submitter keyword: rrDLBCL,R-CHO, DLBCL

Contact List

Allan Stensballe
contact affiliation	Aalborg University
contact email	as@hst.aau.dk
lab head
Allan Stensballe
contact affiliation	Aalborg University
contact email	as@hst.aau.dk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD064483
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD064483

PRIDE project URI

Repository Record List

[ + ]