PXD064431
PXD064431 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | UBE2T mediated HP1α ubiquitination enhances nucleolar function and promote the progression of IDH1/TP53-mutant glioma |
| Description | High-grade glioma is the most aggressive form of primary brain tumor, characterized by rapid progression and a grim prognosis. The presence of mutations in the IDH1 and TP53 is associated with a specific molecular phenotype in glioma, and their interaction is a potential target for therapy. |
| HostingRepository | iProX |
| AnnounceDate | 2025-05-30 |
| AnnouncementXML | Submission_2025-05-29_20:20:26.952.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Fengqi Zhou |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-05-29 20:16:46 | ID requested | |
| ⏵ 1 | 2025-05-29 20:20:27 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: glioma, IDH1 mutation, TP53 mutation, UBE2T, nucleolar function |
Contact List
| Tianfu Yu | |
|---|---|
| contact affiliation | Department of Neurosurgery, The Affiliated Drum Tower Hospital, School of Medicine, Nanjing University |
| contact email | neurotianfu@126.com |
| lab head | |
| Fengqi Zhou | |
| contact affiliation | Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University |
| contact email | zhoufengqi@zju.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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