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PXD064323

PXD064323 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMass spectrometry-based proteomics to study gastric cancer progression: pathophysiological molecular characterization
DescriptionThis study employs a proteomic approach to characterize early pathological stages of GC, including chronic gastritis (CG), intestinal metaplasia and low-grade dysplasia (MI-DBG), and advanced stages such as EGC and GC. Specifically, this research seeks to (i) identify stage-specific proteomic signatures by determining differentially expressed proteins (DEPs) across lesional and non-lesional tissues at different stages of the disease progression, (ii) explore molecular pathways by analyzing disrupted biological processes to understand their role in GC progression; (iii) characterize shared and distinct protein deregulation patterns between early and advanced stages; and (iv) develop a systems biology framework to map protein interactions and identify key molecular regulators driving GC progression. These insights may contribute to a deeper understanding of GC pathogenesis and could potentially serve for early detection strategies and therapeutic interventions.
HostingRepositoryjPOST
AnnounceDate2026-03-17
AnnouncementXMLSubmission_2026-03-17_07:37:33.602.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJoaquin Fernandez-Irigoyen
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-carboxamidomethyl-L-cysteine; N6-acetyl-L-lysine; 2-pyrrolidone-5-carboxylic acid (Gln); L-methionine sulfoxide
Instrumentinstrument
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-05-27 00:53:34ID requested
12026-03-17 07:37:34announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Gastric cancer, proteomics
Contact List
Joaquin Fernandez-Irigoyen
lab head
Joaquin Fernandez-Irigoyen
contact affiliationNavarrabiomed
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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