PXD064296

PXD064296 is an original dataset announced via ProteomeXchange.

Title	Cryo-EM of cardiac AL-224L amyloid reveals shared features in l6 light chain fibril folds
Description	Structural characterization of an amyloid fibril from a patient afected by cardiac light chain amyloidosis.
HostingRepository	PRIDE
AnnounceDate	2026-01-23
AnnouncementXML	Submission_2026-01-23_01:20:10.458.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Francesca Lavatelli
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2025-05-26 01:51:26	ID requested
⏵ 1	2026-01-23 01:20:11	announced

10.1016/j.jmb.2025.169591;

Hicks CW, Prokaeva T, Spencer B, Jayaraman S, Huda N, Wong S, Chen H, Sanchorawala V, Lavatelli F, Gursky O, 6 Light Chain Fibrils. J Mol Biol, 438(3):169591(2026) [pubmed]

submitter keyword: None

Francesca Lavatelli
contact affiliation	University of Pavia, Dept. of Molecular Medicine
contact email	francesca.lavatelli@unipv.it
lab head
Francesca Lavatelli
contact affiliation	University of Pavia
contact email	francesca.lavatelli@unipv.it
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD064296

PRIDE project URI

• PRIDE
  1. PXD064296
     1. Label: PRIDE project
     2. Name: Cryo-EM of cardiac AL-224L amyloid reveals shared features in l6 light chain fibril folds