PXD064136

PXD064136 is an original dataset announced via ProteomeXchange.

Title	Proteome alterations in Filamin A deficient granulosa cell tumor-derived KGN cells.
Description	The goal of the study was to evaluate consequences of Filamin A deficiency in granulosa cell tumor-derived KGN cells. Therefore, proteomes of WT and Filamin A deficient KGN cells were quantitatively compared using LC-MS/MS.
HostingRepository	PRIDE
AnnounceDate	2026-05-22
AnnouncementXML	Submission_2026-05-22_06:39:38.666.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Thomas Fröhlich
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2025-05-21 02:34:33	ID requested
⏵ 1	2026-05-22 06:39:39	announced

10.1186/s40659-026-00686-x;

Jiang Y, Caban KM, Peitzsch M, Herrmann C, Mayr D, St, ö, ckl JB, Fr, ö, hlich T, Mayerhofer A, M, ü, ller-Taubenberger A, Welter H, Knockout of filamin A in KGN granulosa tumor cells impairs proliferation, cell cycle progression, migration, and cytoskeletal organization under mechanical stress. Biol Res, 59(1):(2026) [pubmed]

submitter keyword: Filamin A, KGN-cells,Ovarian cancer, granulosa cells

Thomas Fröhlich
contact affiliation	Dr. Thomas Fröhlich Ludwig-Maximilians-Universität München Genzentrum Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 D-81377 München
contact email	frohlich@genzentrum.lmu.de
lab head
Thomas Fröhlich
contact affiliation	Ludwig-Maximilians-Universität München Genzentrum Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 81377 Munich
contact email	frohlich@genzentrum.lmu.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD064136

PRIDE project URI

• PRIDE
  1. PXD064136
     1. Label: PRIDE project
     2. Name: Proteome alterations in Filamin A deficient granulosa cell tumor-derived KGN cells.