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PXD064042

PXD064042 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative proteomic analysis of UUO-14d kidneys from Adamts18+/+ versus Adamts18−/− mice using label-free LC-MS/MS
DescriptionThis project aims to investigate the proteomic differences between Adamts18+/+ and Adamts18−/− mice in response to unilateral ureteral obstruction (UUO) for 14 days. Kidney tissues were collected from both genotypes and subjected to quantitative proteomic analysis using label-free LC-MS/MS-based techniques. The workflow included protein extraction, trypsin digestion, peptide separation, and mass spectrometric analysis. Differentially expressed proteins were identified to explore the molecular mechanisms associated with Adamts18 deficiency in renal fibrosis under UUO conditions.
HostingRepositoryiProX
AnnounceDate2025-05-19
AnnouncementXMLSubmission_2025-05-18_23:40:17.445.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMin Wang
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-05-18 23:39:55ID requested
12025-05-18 23:40:17announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Mouse, UUO, Adamts18 knockout, Kidney, 14 days, Label-free Quantitative Proteomics, LC-MS/MS
Contact List
Wei Zhang
contact affiliationEast China Normal University
contact emailwzhang@sat.ecnu.edu.cn
lab head
Min Wang
contact affiliationEast China Normal University
contact email52261300023@stu.ecnu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI