PXD064042
PXD064042 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Quantitative proteomic analysis of UUO-14d kidneys from Adamts18+/+ versus Adamts18−/− mice using label-free LC-MS/MS |
Description | This project aims to investigate the proteomic differences between Adamts18+/+ and Adamts18−/− mice in response to unilateral ureteral obstruction (UUO) for 14 days. Kidney tissues were collected from both genotypes and subjected to quantitative proteomic analysis using label-free LC-MS/MS-based techniques. The workflow included protein extraction, trypsin digestion, peptide separation, and mass spectrometric analysis. Differentially expressed proteins were identified to explore the molecular mechanisms associated with Adamts18 deficiency in renal fibrosis under UUO conditions. |
HostingRepository | iProX |
AnnounceDate | 2025-05-19 |
AnnouncementXML | Submission_2025-05-18_23:40:17.445.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Min Wang |
SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2025-05-18 23:39:55 | ID requested | |
⏵ 1 | 2025-05-18 23:40:17 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Mouse, UUO, Adamts18 knockout, Kidney, 14 days, Label-free Quantitative Proteomics, LC-MS/MS |
Contact List
Wei Zhang | |
---|---|
contact affiliation | East China Normal University |
contact email | wzhang@sat.ecnu.edu.cn |
lab head | |
Min Wang | |
contact affiliation | East China Normal University |
contact email | 52261300023@stu.ecnu.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |