⮝ Full datasets listing
PXD063913
PXD063913 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Pancreatic cancer cell samples (DDA) |
| Description | Whole proteome measurement to determine selectivitiy profile for compound NK250 in pancreatic cancer as well as determining downstream signaling effects of DUB inhibition and degradation. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-05-18 |
| AnnouncementXML | Submission_2026-05-18_05:39:42.470.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Farnusch Kaschani |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-05-13 23:08:29 | ID requested | |
| 1 | 2026-04-21 00:08:49 | announced | |
| ⏵ 2 | 2026-05-18 05:39:43 | announced | 2026-05-18: Updated project metadata. |
Publication List
| 10.1038/s41467-026-72295-x; |
| Klink N, Urban S, Seier JA, Adhikari B, Schwalm MP, M, ü, ller J, Dorsch M, Steinbach P, Jung J, Vogt M, Kaschani F, Koch J, F, ü, hrer S, Kaiser M, Schulze N, Knapp S, Wolf E, Paschen A, Gr, ü, ner BM, Gersch M, Targeted degradation of USP7 in solid cancer cells reveals distinct effects of deubiquitinase degraders and inhibitors. Nat Commun, 17(1):(2026) [pubmed] |
Keyword List
| submitter keyword: LC-MS, pull-down, USP7-targeting degrader,Panc89, PROTAC |
Contact List
| Farnusch Kaschani | |
|---|---|
| contact affiliation | Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany |
| contact email | farnusch.kaschani@uni-due.de |
| lab head | |
| Farnusch Kaschani | |
| contact affiliation | University Duisburg-Essen |
| contact email | farnusch.kaschani@uni-due.de |
| dataset submitter | |
Full Dataset Link List
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD063913 |
| PRIDE project URI |
Repository Record List
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