PXD063887

PXD063887 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Antibody-drug conjugate stability probed by variable-temperature electrospray ionization mass spectrometry
Description	The stability of hinge-deleted and mutated IgG4, as well as lysine- (Trastuzumab emtansine) and cysteine-based ADCs (Enfortumab vedotin, Brentuximab vedotin) was probed with vT-ESI-MS.
HostingRepository	PRIDE
AnnounceDate	2025-05-22
AnnouncementXML	Submission_2025-05-21_19:04:35.433.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dina Schuster
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Thermo Fisher Scientific instrument model

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-05-13 08:03:13	ID requested
⏵ 1	2025-05-21 19:04:35	announced

Publication List

10.1021/JASMS.5C00109;

10.1021/JASMS.5C00109;

Keyword List

submitter keyword: vT-ESI-MS, antibody-drug conjugate,antibody, native MS, ADC

submitter keyword: vT-ESI-MS, antibody-drug conjugate,antibody, native MS, ADC

Contact List

Albert J. R. Heck
contact affiliation	Biomolecular Mass Spectrometry & Proteomics, Bijvoet Center for Biomolecular Research & Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.; Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands
contact email	a.j.r.heck@uu.nl
lab head
Dina Schuster
contact affiliation	Utrecht University
contact email	d.schuster1@uu.nl
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD063887
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD063887

PRIDE project URI

Repository Record List

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