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PXD063870

PXD063870 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDIA-based Proteomic Profiling of FFPE Medulloblastoma Tissues from Indian Patient Cohort
DescriptionThis dataset includes Data-Independent Acquisition (DIA) raw files generated from FFPE medulloblastoma tissue samples collected at NIMHANS, India. Samples were subgrouped into WNT, SHH and non-WNT/non-SHH (NWS) based on immunohistochemical profiling. Deparrafinized tissues were processed using a Filter-Aided Sample Preparation (FASP) protocol, followed by LC-MS/MS analysis on a high-resolution Thermo Scientific Orbitrap Fusion mass spectrometer. DIA acquisition was performed using optimized m/z windows for the samples, and spectral library construction included pooled fraction runs across separate precursor m/z windows. QC pools were run to monitor runwise consistency.
HostingRepositoryjPOST
AnnounceDate2026-07-28
AnnouncementXMLSubmission_2026-07-27_08:21:43.008.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMedha Gayathri Pai
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-carboxamidomethyl-L-cysteine; L-methionine sulfoxide
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-05-12 20:00:48ID requested
12026-07-27 08:21:43announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Medulloblastoma, FFPE proteomics, Data Independent Acquisition, Tumor heterogeneity, SHH subgroup, Non-WNT/non-SHH (NWS)
Contact List
Prof. Sanjeeva Srivastava
lab head
Medha Gayathri Pai
contact affiliationDepartment of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, Maharashtra 400076, India.
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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