PXD063850 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Profiling CTBP2’s genome-wide interactome in murine macrophages in resting state and during LPS-induced inflammation |
Description | We profiled the genome-wide interactome of the co-repressor C-terminal binding protein 2 (CTBP2) in primary murine macrophages (BMDM) in vehicle and LPS conditions after 3 h of stimulation. We find that CTBP2 interacts with the transcription factors NF-κB and AP-1 and forms a corepressor complex that involves KDM1A, the NuRD complex and other co-repressors. |
HostingRepository | PRIDE |
AnnounceDate | 2025-06-08 |
AnnouncementXML | Submission_2025-06-08_00:19:02.560.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Michael Wierer |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2025-05-12 01:40:18 | ID requested | |
⏵ 1 | 2025-06-08 00:19:02 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: LPS, macrophage,CTBP2, inflammation, BMDM, mouse, ChIP-MS |
Contact List
Henriette Uhlenhaut |
contact affiliation | Metabolic Programming, TUM School of Life Sciences, Technical University of Munich, Munich, Bavaria, Germany |
contact email | henriette.uhlenhaut@tum.de |
lab head | |
Michael Wierer |
contact affiliation | Proteomics Research Infrastructure, University of Copenhagen |
contact email | michael.wierer@sund.ku.dk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD063850 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD063850
- Label: PRIDE project
- Name: Profiling CTBP2’s genome-wide interactome in murine macrophages in resting state and during LPS-induced inflammation