PXD063842

PXD063842 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Identifying novel NEDD4-2 interacting proteins
Description	NEDD4-2 is an E3 ubiquitin ligase involved in the regulation of several membrane proteins. This project was designed to identify new NEDD4-2-regulated substrates in the mouse cortical collecting duct cell line.
HostingRepository	PRIDE
AnnounceDate	2025-08-25
AnnouncementXML	Submission_2025-08-24_16:15:29.978.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Laura Dagley
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-05-11 19:29:04	ID requested
⏵ 1	2025-08-24 16:15:30	announced

Publication List

Shabbar M, Manning JA, Lim Y, Shah SS, Sinha D, Nikolic A, Sandow JJ, Kumar S, Phospholipid scramblase 1 (PLSCR1) is a novel substrate of NEDD4-2 (NEDD4L) mediated ubiquitination. Cell Death Discov, 11(1):393(2025) [pubmed]
10.1038/s41420-025-02700-9;

Shabbar M, Manning JA, Lim Y, Shah SS, Sinha D, Nikolic A, Sandow JJ, Kumar S, Phospholipid scramblase 1 (PLSCR1) is a novel substrate of NEDD4-2 (NEDD4L) mediated ubiquitination. Cell Death Discov, 11(1):393(2025) [pubmed]

10.1038/s41420-025-02700-9;

Keyword List

submitter keyword: NEDD4-2

submitter keyword: NEDD4-2

Contact List

Prof. Sharad
contact affiliation	Bradley Distinguished Professor Chair of Cancer Biology & Research Professor of Cell Biology Centre for Cancer Biology University of South Australia
contact email	sharad.kumar@unisa.edu.au
lab head
Laura Dagley
contact affiliation	WEHI
contact email	dagley.l@wehi.edu.au
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD063842
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD063842

PRIDE project URI

Repository Record List

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