PXD063691
PXD063691 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Photocatalytic Proximity Labeling for Mapping Lysosomal Proteome |
Description | This project develops the photocatalytic lysosome-tracking proteome mapping (PLT-PM) method, which uses LysoTracker DND-26 as both a lysosomal tracker and visible-light photocatalyst. The method enables one-step, high-resolution, and low-disruption profiling of the lysosomal proteome without requiring genetic modification or custom dye synthesis. It was applied alongside LC-MS/MS to analyze lysosomal proteome changes during rapamycin and amino acid starvation-induced autophagy, offering a biocompatible and accessible platform to advance lysosome-related research. |
HostingRepository | iProX |
AnnounceDate | 2025-05-03 |
AnnouncementXML | Submission_2025-05-06_20:05:23.802.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Liang Zhang |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2025-05-06 20:05:02 | ID requested | |
⏵ 1 | 2025-05-06 20:05:24 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: photocatalysis, proximity Labeling, proteomics, lysosome |
Contact List
Liang Zhang | |
---|---|
contact affiliation | City University of Hong Kong |
contact email | liangzhang.28@cityu.edu.hk |
lab head | |
Liang Zhang | |
contact affiliation | City University of Hong Kong |
contact email | liangzhang.28@cityu.edu.hk |
dataset submitter |
Full Dataset Link List
iProX dataset URI |