PXD063540

PXD063540 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Immunoprecipitation and Mass Spectrometry Reveals Interactors of CD11b
Description	We aimed to identify CD11b-associated inhibitory receptors,that control phagocytosis when engaged by ligands expressed on cancer cells. CD11b was immunoprecipitated from mouse bone marrow-derived macrophages (BMDMs), and the associated proteins were analyzed using mass spectrometry. A few inhibitory receptors were identified in CD11b immunoprecipitates from wild-type BMDMs, but not from CD18 (the β2 subunit of Mac-1)-deficient BMDMs, which lack CD11b.
HostingRepository	PRIDE
AnnounceDate	2025-09-17
AnnouncementXML	Submission_2025-09-17_08:09:31.259.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jiaxin Li
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Velos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-05-01 12:14:22	ID requested
⏵ 1	2025-09-17 08:09:31	announced

Publication List

10.1038/S41467-025-60456-3;

10.1038/S41467-025-60456-3;

Keyword List

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: Mac-1, CD200R1,CD11b, BMDMs

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project

submitter keyword: Mac-1, CD200R1,CD11b, BMDMs

Contact List

Jiaxin Li and Andre Veillette
contact affiliation	Laboratory of Molecular Oncology1, Institut de recherches cliniques de Montréal (IRCM), Montréal, Québec, Canada H2W1R7; Department of Medicine2, McGill University, Montréal, Québec, Canada H3G 1Y6
contact email	jiaxin.li@mail.mcgill.ca
lab head
Jiaxin Li
contact affiliation	IRCM, McGill University
contact email	jiaxin.li@mail.mcgill.ca
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD063540
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD063540

PRIDE project URI

Repository Record List

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