PXD063422

PXD063422 is an original dataset announced via ProteomeXchange.

Title	Mechanism of Zuogui Wan in ameliorating chronic stress-induced intergenerational transmission of ovarian dysfunction via the complement and coagulation cascade pathway
Description	To systematically identify protein targets interacting with traditional Chinese medicine Zuogui Wan, limited proteolysis mass spectrometry (LiP-MS) was employed as a high-throughput screening platform. To investigate the molecular mechanisms underlying chronic unpredictable mild stress (CUMS)-induced Premature ovarian insufficiency (POI), we performed data-independent acquisition (DIA) quantitative proteomics on ovarian tissues from three generations of rats (Control vs. Model groups).
HostingRepository	iProX
AnnounceDate	2025-04-29
AnnouncementXML	Submission_2025-04-28_23:46:20.195.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xin Li
SpeciesList	scientific name: Rattus rattus; NCBI TaxID: 10117;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-28 23:46:08	ID requested
⏵ 1	2025-04-28 23:46:20	announced

Dataset with its publication pending

submitter keyword: Zuogui Wan (ZGW)，Premature ovarian insufficiency，Limited proteolysis-coupled mass spectrometry，Data-Independent Acquisition Proteomics

Min Zhao
contact affiliation	Basic Medical Division, Hubei University of Chinese Medicine
contact email	zmin13@hbtcm.edu.cn
lab head
Xin Li
contact affiliation	SpecAlly Life Technology Co., Ltd.
contact email	lixin@spec-ally.com
dataset submitter

iProX dataset URI