PXD063306 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | PirB-CTF LC-MS/MS in hippocampus |
| Description | Our result indicated PirB could undergo proteolytic process, generating a C-terminal fragment (PirB-CTF). We found PirB-CTF can translocates to the Golgi apparatus, disrupting Golgi-dependent protein transport. To investigate the novel binding partners which mediated the effect of PirB-CTF, we used mass spectrometry analysis. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-06-08 |
| AnnouncementXML | Submission_2026-06-07_16:13:01.648.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | wubo Han |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-04-24 21:12:29 | ID requested | |
| ⏵ 1 | 2026-06-07 16:13:03 | announced | |
Publication List
| 10.1186/s40035-026-00553-5; |
| Han WB, Liu XD, Tang CF, Zheng J, Xu TL, Xu NJ, Sun S, Persistent PirB cleavage drives Golgi-directed trafficking deficits underlying neurodegeneration. Transl Neurodegener, 15(1):(2026) [pubmed] |
Keyword List
| submitter keyword: mouse, PirB, hippocampus, Golgi apparatus, C-terminal fragment |
Contact List
| Suya Sun |
|---|
| contact affiliation | Department of Neurology and Institute of Neurology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. |
| contact email | sunsuya@shsmu.edu.cn |
| lab head | |
| wubo Han |
|---|
| contact affiliation | Department of Neurology and Institute of Neurology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. |
| contact email | 349417183@qq.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD063306 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD063306
- Label: PRIDE project
- Name: PirB-CTF LC-MS/MS in hippocampus
