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PXD063263

PXD063263 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlecTAGE5/MEA6 regulates LBR transport to maintain nuclear envelope integrity and safeguard against aging
DescriptionIP-MS of fused MEA6-GFP and the control sample were performed. For MS analyses, peptides were resuspended in 0.1% FA and analyzed by LTQ Orbitrap Elite mass spectrometer (ThermoFisher Scientific) coupled online to an Easy-nLC 1000 (Thermo Fisher Scientific) in the data-dependent mode.
HostingRepositoryiProX
AnnounceDate2025-04-24
AnnouncementXMLSubmission_2025-11-28_00:24:00.096.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterFuqiang Yang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-04-23 22:06:35ID requested
12025-04-23 22:06:56announced
22025-11-28 00:24:01announced2025-11-28: Add info
Publication List
Wang Y, Sun P, Yang F, Ma T, Fan J, Shi L, Li N, Gao F, He K, Xu Z, cTAGE5/MEA6 Regulates LBR Localization to Maintain Nuclear Envelope Integrity and Safeguard Against Aging. Aging Cell, 24(10):e70185(2025) [pubmed]
Keyword List
submitter keyword: cTAGE5/MEA6, nuclear envelope assembly, senescence, LBR
Contact List
Zhiheng Xu
contact affiliationInstitute of Genetics and Developmental Biology
contact emailzhxu@genetics.ac.cn
lab head
Fuqiang Yang
contact affiliationInstitute of Genetics and Developmental Biology
contact emailfuqiangyang@genetics.ac.cn
dataset submitter
Full Dataset Link List
iProX dataset URI