PXD063213

PXD063213 is an original dataset announced via ProteomeXchange.

Title	YKT6 is essential for male fertility by promoting meiosis progression through vesicular transport regulation during spermatogenesis of mice
Description	The tetraploid spermatocytes of postnatal days (PD) 16 Ykt6-Ctrl and Ykt6-cKO mice obtained by fluorescence-activated cell sorting were subjected to proteomics analysis. After three rinses with phosphate-buffered saline (PBS), the samples were gathered into tubes containing lysis buffer, flash frozen with liquid nitrogen and transferred to a -80 ℃ freezer. The samples were transported on dry ice to the National Center for Protein Sciences at Peking University, Beijing, where they underwent quantitative proteomic determination.
HostingRepository	iProX
AnnounceDate	2025-04-22
AnnouncementXML	Submission_2026-02-02_23:14:19.975.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jie Cen
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-22 21:27:40	ID requested
1	2025-04-22 21:27:52	announced
⏵ 2	2026-02-02 23:14:21	announced	2026-02-03: Add info.

Cen J, Yu X, Wang Z, Liu W, Xu J, Fang Q, Gao F, Cao Y, Liu H, YKT6 Is Essential for Male Fertility by Promoting Meiosis Progression During Spermatogenesis of Mice. Cell Prolif, 59(1):e70079(2026) [pubmed]

submitter keyword: YKT6, spermatogenesis, meiotic arrest, vesicular transport, intercellular bridge

Hongbin Liu
contact affiliation	Shandong University
contact email	hongbin_sduivf@aliyun.com
lab head
Jie Cen
contact affiliation	Shandong University
contact email	cenjie@mail.sdu.edu.cn
dataset submitter

iProX dataset URI