PXD062918

PXD062918 is an original dataset announced via ProteomeXchange.

Title	Differing proteome responses to ocean acidification between two common pocilloporid corals
Description	Ocean acidification increasingly threatens coral reef ecosystems by challenging calcifi-cation processes fundamental to reef accretion. Yet, many corals continue to calcify under elevated pCO₂, suggesting species-specific physiological plasticity and potential cellular compensations. Here, we investigate the proteomic responses of two common pocilloporid corals, Stylophora pistillata and Pocillopora damicornis, to moderate (~940 ppm) and high (~2,800 ppm) pCO₂ over a two-month period. Using label-free quantita-tive proteomics, we identify changes in protein abundances compared to control con-ditions (~480 ppm) and infer functional shifts that underlie their respective responses to acidification. S. pistillata exhibited extensive proteomic restructuring under high pCO₂, marked by downregulation of metabolic pathways and concurrent upregulation of ion transporters, cytoskeletal elements, and stress response proteins, suggesting a meta-bolically costly but flexible strategy to sustain calcification. In contrast, P. damicornis showed fewer and more moderate proteomic changes, with adjustments in structural proteins and redox regulation, indicating a more restrained acclimatization strategy. These divergent responses highlight contrasting modes of resistance (plasticity versus stability). In direct context to physiological and geochemical data, our findings reveal cellular mechanisms of calcification control and underscore the utility of proteomics in coral ecophysiology, offering new insights into species-specific vulnerability and po-tential adaptive capacities under future ocean conditions.
HostingRepository	PRIDE
AnnounceDate	2026-03-02
AnnouncementXML	Submission_2026-03-02_08:06:17.035.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Laxmikanth Kollipara
SpeciesList	scientific name: Stylophora pistillata; NCBI TaxID: NEWT:50429; scientific name: Pocillopora damicornis/Symbiodinium spp. mixed library; NCBI TaxID: NEWT:590651;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos; Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-14 02:34:37	ID requested
⏵ 1	2026-03-02 08:06:17	announced

10.1007/S00338-025-02801-Y;

submitter keyword: None

Prof. Dr.
contact affiliation	Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Otto-Hahn-Str. 6b 44227 Dortmund, Germany P: +49 (0)2 31.13 92-100 www.isas.de LinkedIn: leibniz-institut-isas Bluesky: @isas-leibniz.bsky.social
contact email	albert.sickmann@isas.de
lab head
Laxmikanth Kollipara
contact affiliation	Leibniz – Institut für Analytische Wissenschaften - ISAS - e.V.
contact email	laxmikanth.kollipara@isas.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD062918

PRIDE project URI

• PRIDE
  1. PXD062918
     1. Label: PRIDE project
     2. Name: Differing proteome responses to ocean acidification between two common pocilloporid corals