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PXD062749

PXD062749 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePhosphoproteomic Profiling of Acute Myocardial Infarction Serum Samples
DescriptionAcute myocardial infarction (AMI) involves complex molecular events, including alterations in protein phosphorylation. In this study, we performed a comparative phosphoproteomic analysis of serum samples from AMI patients and healthy controls to identify AMI-associated phosphorylation signatures. Serum samples from eight AMI patients and two pooled controls underwent high-abundance protein depletion, enzymatic digestion with Trypsin/Lys-C, and phosphopeptide enrichment using Fe-NTA spin columns. Enriched phosphopeptides were analyzed by LC-MS/MS using a Q Exactive™ HF-X Orbitrap system.
HostingRepositoryPRIDE
AnnounceDate2026-05-25
AnnouncementXMLSubmission_2026-05-24_16:39:07.924.xml
DigitalObjectIdentifierhttps://doi.org/10.6019/PXD062749
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterMerve Oztug
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListphosphorylated residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-04-08 11:18:44ID requested
12026-05-24 16:39:08announced
Publication List
10.55730/1300-0144.6194;
10.6019/PXD062749;
Ö, ztu, ğ M, A, ş, icio, ğ, lu M, Altinkaynak K, Kilin, ç E, Serum phosphoproteome alterations associated with cardiac troponin I levels in acute myocardial infarction. Turk J Med Sci, 56(2):613-623(2026) [pubmed]
Keyword List
submitter keyword: Human, AMI, phosphoproteomics
Contact List
Merve Oztug
contact affiliationNational Metrology Institute of TURKEY
contact emailmerve.oztug@tubitak.gov.tr
lab head
Merve Oztug
contact affiliationTUBITAK UME
contact emailmerve.oztug@tubitak.gov.tr
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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