PXD062735

PXD062735 is an original dataset announced via ProteomeXchange.

Title	Social Hierarchy alters Drug Reward and the Protein Phosphorylation in the Nucleus Accumbens
Description	Protein phosphorylation, a type of post-translational modification (PTM), has been identified in the addiction process. However, its role in social hierarchy remains poorly understood. In this study, we used the tube test to classify rats as dominants or subordinates. In the CPP paradigm, subordinates exhibited a higher susceptibility to addiction. Quantitative phosphoproteomic analysis revealed distinct phosphoproteomic profiles in the Nucleus Accumbens between these groups.
HostingRepository	PRIDE
AnnounceDate	2025-04-09
AnnouncementXML	Submission_2025-04-08_19:23:57.322.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Liang Xu
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	phosphorylated residue
Instrument	timsTOF Pro; LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-08 07:44:30	ID requested
⏵ 1	2025-04-08 19:23:57	announced

Dataset with its publication pending

submitter keyword: LC-MSMS,rat, Nucleus Accumbens

Wei Xu
contact affiliation	Faculty of Life and Health Sciences, Shenzhen University of Advanced Technology
contact email	freefresh2000@163.com
lab head
Liang Xu
contact affiliation	West China School of Public Health and West China Fourth Hospital, Sichuan University
contact email	l.xu@siat.ac.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD062735

PRIDE project URI

• PRIDE
  1. PXD062735
     1. Label: PRIDE project
     2. Name: Social Hierarchy alters Drug Reward and the Protein Phosphorylation in the Nucleus Accumbens