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PXD062723

PXD062723 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleComprehensive Phenotypic and Proteomic Analyses of Human Reticulocyte Maturation
DescriptionErythropoiesis is the fabrication process of erythrocytes and is located in bone marrow. After commitment, erythroid progenitors differentiate into erythroblasts and generate immature reticulocytes. Reticulocytes are then released in the blood circulation and mature into ertythrocytes. While absolute quantification of the proteome of erythroblasts, circulating reticulocytes and ertythrocytes have already been studied, a few is known about immature reticulocytes located in the bone marrow. Here, we mesured the absolute quantification of immature bone marrow reticulocytes and compare it to mature circulating reticulocytes and erythrocytes.
HostingRepositoryPRIDE
AnnounceDate2025-11-12
AnnouncementXMLSubmission_2025-11-12_09:39:41.520.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMarjorie Leduc
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-04-08 03:34:14ID requested
12025-11-12 09:39:42announced
Publication List
10.1016/J.BRCI.2025.100012;
Keyword List
submitter keyword: bone marrow, red cells,Reticulocyte, absolute quantification
Contact List
Lionel Blanc
contact affiliationInstitute of Molecular Medicine, Feinstein Institutes for Medical Research, Manhasset, New York NY 11030 USA Department of Molecular Medicine and Pediatrics, Zucker School of Medicine at Hofstra/Northwell, Hempstead NY 11549 USA Laboratory of Excellence GREx
contact emailLblanc@northwell.edu
lab head
Marjorie Leduc
contact affiliationPlateforme protéomique 3P5, Université de Paris, Institut Cochin, INSERM, CNRS,
contact emailmarjorie.leduc@inserm.fr
dataset submitter
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Dataset FTP location
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