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PXD062707

PXD062707 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic and Acetylome Alterations in Obesity-related Osteoarthritic Mouse Cartilage
DescriptionMale mice aged 4 weeks were housed under controlled conditions and assigned to either a normal diet or a high-fat diet for 16 weeks to establish an obesity model. At 12 weeks, osteoarthritis was induced using the destabilization of the medial meniscus procedure under anesthesia, while sham-operated mice served as controls. Eight weeks post-surgery, tibial cartilage tissues were collected, ensuring surrounding tissues were removed under a microscope. Tissues from 3-5 mice per group were pooled, and flash-frozen for subsequent lipidomic, proteomic, and acetylome analyses.
HostingRepositoryiProX
AnnounceDate2025-04-08
AnnouncementXMLSubmission_2025-04-08_00:17:09.598.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterShuying Shen
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListacetylated residue
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-04-08 00:16:54ID requested
12025-04-08 00:17:09announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Proteomic, Acetylome
Contact List
Shunwu Fan
contact affiliationSir Run Run Shaw Hospital, Zhejiang University School of Medicin
contact emailshunwu_fan@zju.edu.cn
lab head
Shuying Shen
contact affiliationSir Run Run Shaw Hospital, Zhejiang University School of Medicine
contact email11207057@zju.edu.cn
dataset submitter
Full Dataset Link List
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