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PXD062661

PXD062661 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSingle Amino-acid Polymorphisms of Human Gut Ecosystem
DescriptionSingle nucleotide polymorphisms (SNPs) are the most common type of genetic variation in gut microbial metagenome and host genome but they could not adequately represent the protein-level variants. Single amino-acid polymorphisms (SAP) derived from non-synonymous SNPs can cause functional changes of proteins and are important forces of adaption. However, SAP remain quite unexplored for human gut microbiome. Here, we present a comprehensive large-scale analysis of SAP in the gut ecosystem, introducing a rigorous computational pipeline for detecting such protein variation from 992 published human metaproteomes.
HostingRepositoryiProX
AnnounceDate2025-04-05
AnnouncementXMLSubmission_2025-04-07_00:13:00.924.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZhixiang Yan
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-04-07 00:12:44ID requested
⏵ 12025-04-07 00:13:01announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Single Amino-acid Polymorphisms, Gut microbiome
Contact List
Zhixiang Yan
contact affiliationSun Yat-sen University
contact emailyanzhx3@mail.sysu.edu.cn
lab head
Zhixiang Yan
contact affiliationSun Yat-sen University
contact emailyanzhx3@mail.sysu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI

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