PXD062651 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Cell division protein CdpA organises and anchors the midcell ring in haloarchaea |
Description | Many archaea appear to divide through the coordinated activities of two FtsZ homologues (FtsZ1 and FtsZ2) and another bacterial cell division homologue (SepF), which are part of the midcell division ring. Here, we identify an additional protein (HVO_0739, renamed Cell Division Protein A, CdpA) that is required for normal cell division in Haloferax volcanii, with homologues in other Haloarchaea. Protein localization and dynamics analyses, protein domain function studies, pull-down assays, and multimer structure predictions suggest that CdpA is part of a membrane complex that tethers FtsZ2 and other division proteins to the midcell membrane. |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-31 |
AnnouncementXML | Submission_2025-05-31_02:11:54.244.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Iain Duggin |
SpeciesList | scientific name: Haloferax volcanii DS2; NCBI TaxID: 309800; |
ModificationList | S-carboxamidoethyl-L-cysteine; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2025-04-06 21:43:48 | ID requested | |
⏵ 1 | 2025-05-31 02:11:54 | announced | |
Publication List
Keyword List
submitter keyword: Archaea |
Cell Division |
Pull-down |
FtsZ |
Interaction |
Contact List
Iain Duggin |
contact affiliation | Australian Institute for Microbiology and Infection, University of Technology Sydney, Australia |
contact email | Iain.Duggin@uts.edu.au |
lab head | |
Iain Duggin |
contact affiliation | University of Technology Sydney |
contact email | Iain.Duggin@uts.edu.au |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD062651
- Label: PRIDE project
- Name: Cell division protein CdpA organises and anchors the midcell ring in haloarchaea