⮝ Full datasets listing

PXD062651

PXD062651 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCell division protein CdpA organises and anchors the midcell ring in haloarchaea
DescriptionMany archaea appear to divide through the coordinated activities of two FtsZ homologues (FtsZ1 and FtsZ2) and another bacterial cell division homologue (SepF), which are part of the midcell division ring. Here, we identify an additional protein (HVO_0739, renamed Cell Division Protein A, CdpA) that is required for normal cell division in Haloferax volcanii, with homologues in other Haloarchaea. Protein localization and dynamics analyses, protein domain function studies, pull-down assays, and multimer structure predictions suggest that CdpA is part of a membrane complex that tethers FtsZ2 and other division proteins to the midcell membrane.
HostingRepositoryPRIDE
AnnounceDate2025-05-31
AnnouncementXMLSubmission_2025-05-31_02:11:54.244.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterIain Duggin
SpeciesList scientific name: Haloferax volcanii DS2; NCBI TaxID: 309800;
ModificationListS-carboxamidoethyl-L-cysteine; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-04-06 21:43:48ID requested
12025-05-31 02:11:54announced
Publication List
10.1038/S41467-025-60079-8;
Keyword List
submitter keyword: Archaea
Cell Division
Pull-down
FtsZ
Interaction
Contact List
Iain Duggin
contact affiliationAustralian Institute for Microbiology and Infection, University of Technology Sydney, Australia
contact emailIain.Duggin@uts.edu.au
lab head
Iain Duggin
contact affiliationUniversity of Technology Sydney
contact emailIain.Duggin@uts.edu.au
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD062651
PRIDE project URI
Repository Record List
[ + ]