PXD062651

PXD062651 is an original dataset announced via ProteomeXchange.

Title	Cell division protein CdpA organises and anchors the midcell ring in haloarchaea
Description	Many archaea appear to divide through the coordinated activities of two FtsZ homologues (FtsZ1 and FtsZ2) and another bacterial cell division homologue (SepF), which are part of the midcell division ring. Here, we identify an additional protein (HVO_0739, renamed Cell Division Protein A, CdpA) that is required for normal cell division in Haloferax volcanii, with homologues in other Haloarchaea. Protein localization and dynamics analyses, protein domain function studies, pull-down assays, and multimer structure predictions suggest that CdpA is part of a membrane complex that tethers FtsZ2 and other division proteins to the midcell membrane.
HostingRepository	PRIDE
AnnounceDate	2025-05-31
AnnouncementXML	Submission_2025-05-31_02:11:54.244.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Iain Duggin
SpeciesList	scientific name: Haloferax volcanii DS2; NCBI TaxID: 309800;
ModificationList	S-carboxamidoethyl-L-cysteine; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-06 21:43:48	ID requested
⏵ 1	2025-05-31 02:11:54	announced

10.1038/S41467-025-60079-8;

submitter keyword: Archaea

Cell Division

Pull-down

FtsZ

Interaction

Iain Duggin
contact affiliation	Australian Institute for Microbiology and Infection, University of Technology Sydney, Australia
contact email	Iain.Duggin@uts.edu.au
lab head
Iain Duggin
contact affiliation	University of Technology Sydney
contact email	Iain.Duggin@uts.edu.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD062651

PRIDE project URI

• PRIDE
  1. PXD062651
     1. Label: PRIDE project
     2. Name: Cell division protein CdpA organises and anchors the midcell ring in haloarchaea