PXD062650

PXD062650 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	https://edelivery.oracle.com/akam/otn/java/jdk/8u202-b08/1961070e4c9b4e26a04e7f5a083f551e/jre-8u202-windows-i586-iftw.exe
Description	This study examines how aging influences the proteomic landscape of human spermatozoa. Proteomic analysis was done on sperm samples from three groups of normal, fertile men: young adults (21–30 years), late adults (31–40 years), and advanced age (41–51 years). The analysis revealed dynamic age-related alterations in human sperm proteins potentially impacting key sperm physiological functions such as motility, metabolism, and fertilization.
HostingRepository	PRIDE
AnnounceDate	2025-07-21
AnnouncementXML	Submission_2025-07-20_16:16:28.677.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD062650
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Ayodele Alaiya
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue; iodoacetamide derivatized residue
Instrument	Synapt MS

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-06 17:38:18	ID requested
⏵ 1	2025-07-20 16:16:29	announced

Publication List

10.6019/PXD062650;
10.3390/ijms26136099;
Beg MA, Ismail AO, Alaiya A, Khan FA, Hamoda TAA, Sheikh IA, Sharma P, Baothman OM, Alkhzaim AH, Shinwari Z, Abuzinadah RF, Mohammed A, Assiri AM, Abuzenadah AM, Memili E, Feugang JM, Age-Associated Proteomic Changes in Human Spermatozoa. Int J Mol Sci, 26(13):(2025) [pubmed]

10.6019/PXD062650;

10.3390/ijms26136099;

Beg MA, Ismail AO, Alaiya A, Khan FA, Hamoda TAA, Sheikh IA, Sharma P, Baothman OM, Alkhzaim AH, Shinwari Z, Abuzinadah RF, Mohammed A, Assiri AM, Abuzenadah AM, Memili E, Feugang JM, Age-Associated Proteomic Changes in Human Spermatozoa. Int J Mol Sci, 26(13):(2025) [pubmed]

Keyword List

submitter keyword: proteomics, LC-MS/MS.,human, aging, spermatozoa

submitter keyword: proteomics, LC-MS/MS.,human, aging, spermatozoa

Contact List

Dr. Ayodele Alaiya
contact affiliation	King Faisal Specialist Hospital and Research Center
contact email	aalaiya@kfshrc.edu.sa
lab head
Ayodele Alaiya
contact affiliation	Therapeutics & Biomarker Discovery for Clinical Applications, Stem Cell Program, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
contact email	aalaiya@kfshrc.edu.sa
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD062650
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD062650

PRIDE project URI

Repository Record List

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