PXD062648

PXD062648 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic Profiling of Rabbit Kidney Cells Infected with Equine Herpesvirus 8
Description	Equine herpesvirus type 8 (EHV-8), a member of the alpha herpesvirus subfamily, is a significant pathogen in donkeys, causing abortion and respiratory infections, which result in considerable economic losses within the equine industry. Despite its importance, limited research has been conducted on the molecular response to EHV-8 in donkeys. The present study investigated the host cell response to EHV-8 infection in Rabbit kidney (RK-13) cells through transcriptomic and proteomic approaches. Our findings identified several candidate genes and proteins, along with their associated signaling pathways, involved in the cellular response to EHV-8 infection in this in vitro model. However, because RK-13 cells may not accurately replicate viral-host interactions in equine species, additional in vivo studies in horses and donkeys are necessary to achieve a more thorough understanding of viral pathogenesis in these animals.
HostingRepository	PRIDE
AnnounceDate	2025-06-02
AnnouncementXML	Submission_2025-06-01_16:07:19.768.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yanfei Ji
SpeciesList	scientific name: Leporidae; NCBI TaxID: 9979;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-06 04:58:49	ID requested
⏵ 1	2025-06-01 16:07:20	announced

Publication List

10.3390/v17050647;
Ji Y, Xu D, Si W, Zhang Y, Khan MZ, Zhao X, Liu W, Transcriptomic and Proteomic Profiling of Rabbit Kidney Cells Infected with Equine Herpesvirus 8. Viruses, 17(5):(2025) [pubmed]

10.3390/v17050647;

Ji Y, Xu D, Si W, Zhang Y, Khan MZ, Zhao X, Liu W, Transcriptomic and Proteomic Profiling of Rabbit Kidney Cells Infected with Equine Herpesvirus 8. Viruses, 17(5):(2025) [pubmed]

Keyword List

submitter keyword: EHV-8,RK-13

submitter keyword: EHV-8,RK-13

Contact List

Yanfei Ji
contact affiliation	College of Agriculture and Biology of LCU
contact email	jiyanfei0125@163.com
lab head
Yanfei Ji
contact affiliation	College of Agriculture and Biology of LCU
contact email	jiyanfei0125@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD062648
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD062648

PRIDE project URI

Repository Record List

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