PXD062605 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteome Profiling Among Aging Cell Lines |
| Description | Characterization of the proteome provides direct information on disease-associated pathways during the onset and progression of Alzheimer’s Disease (AD). In this project, we employed high-resolution mass spectrometry to quantify the proteomes of AD cell cultures using multiplexed quantification. The following phenotypes were measured: Control (Nt), lamin A mutation (La), progerin (Pg), classical AD mutation (AppNt), AD mutation with lamin A (AppLa), and AD mutation with progerin (AppPg). |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-12 |
| AnnouncementXML | Submission_2026-01-11_22:12:18.728.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Peter Nemes |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; phosphorylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-04-04 06:45:21 | ID requested | |
| ⏵ 1 | 2026-01-11 22:12:19 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: neuroinflammation, proteomics, progeria, mass spectrometry, profiling,Aging, biomarkers |
Contact List
| Peter Nemes |
|---|
| contact affiliation | Chemistry & Biochemistry, University of Maryland, College Park, MD, USA |
| contact email | nemes@umd.edu |
| lab head | |
| Peter Nemes |
|---|
| contact affiliation | University of Maryland, College Park |
| contact email | nemes@umd.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD062605 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD062605
- Label: PRIDE project
- Name: Proteome Profiling Among Aging Cell Lines
