PXD062602 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Phosphoproteomic analysis of bFGF ± C7/Prostetin in D425 cells |
| Description | FGFR signaling is a potent driver of medulloblastoma (MB) progression, driving an invasive phenotype. We explored the impact of a short term bFGF stimulation in D425 MB cells on phosphoproteome level and studied the effect of pretreatment with the FRS2 targeting small molecule C7, or the MAP4K4 inhibitor Prostetin. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-07 |
| AnnouncementXML | Submission_2026-09-06_16:23:55.564.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Martin Baumgartner |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | phosphorylated residue |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-04-04 05:28:32 | ID requested | |
| ⏵ 1 | 2026-09-06 16:23:56 | announced | |
Publication List
| Kopp LL, Versamento D, Ciraulo B, Sch, ö, nholzer MT, Hochuli D, Lin MS, Baumgartner M, Fibroblast growth factor receptor substrate 2 interactome mapping reveals novel candidate interactors associated with migration and invasion. Cell Commun Signal, 24(1):(2026) [pubmed] |
| 10.1186/s12964-026-02943-8; |
Keyword List
| submitter keyword: cancer, pediatric,Phosphoproteomics, MAP4K4, cerebellum, brain cancer, FGFR, FRS2, D425, bFGF, Medulloblastoma, C7, Prostetin |
Contact List
| Martin Baumgartner |
|---|
| contact affiliation | University Children's Hospital Zürich |
| contact email | martin.baumgartner@kispi.uzh.ch |
| lab head | |
| Martin Baumgartner |
|---|
| contact affiliation | University Children's Hospital Zürich |
| contact email | martin.baumgartner@kispi.uzh.ch |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD062602 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD062602
- Label: PRIDE project
- Name: Phosphoproteomic analysis of bFGF ± C7/Prostetin in D425 cells
