PXD062573 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic analysis for microvesicles isolated from uninfected or M.ab-infected RAW 264.7 cells |
| Description | Microvesicles (MVs) are a subtype of extracellular vesicle (EVs) released by cells, which play important roles in cell-cell communication. The role of host cell-derived MVs in host-pathogen interactions remains to be defined in the context of mycobacterial infection. In this study, we characterized MVs that were isolated from mouse RAW 264.7 cells either uninfected or infected with Mycobacterium abscessus (M.ab), one of the most common non-tuberculous mycobacterial (NTM) pathogens in humans, in cell culture. The proteomic profile of purified MVs was determined by mass spectrometry (MS)-based proteomics. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-17 |
| AnnouncementXML | Submission_2025-11-16_16:12:52.857.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Carlyn Guthrie |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-04-03 10:19:50 | ID requested | |
| ⏵ 1 | 2025-11-16 16:12:53 | announced | |
Publication List
| Ramos-Wolfley AD, Speelmon CA, Zhang J, Guthrie CM, Clark OL, Hartson SD, Liu L, Tan X, Cheng Y, Infection. J Proteome Res, 24(11):5523-5535(2025) [pubmed] |
| 10.1021/acs.jproteome.5c00399; |
Keyword List
| submitter keyword: Microvesicles, Mycobacterium abscessus |
Contact List
| Yong Cheng |
|---|
| contact affiliation | Department of Biochemistry and Molecular Biology, Oklahoma State Univerity, Stillwater, OK. |
| contact email | ycheng@okstate.edu |
| lab head | |
| Carlyn Guthrie |
|---|
| contact affiliation | Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma |
| contact email | carlyn.guthrie@okstate.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD062573 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD062573
- Label: PRIDE project
- Name: Proteomic analysis for microvesicles isolated from uninfected or M.ab-infected RAW 264.7 cells
