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PXD062553

PXD062553 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlecoIP proteome of KERP2-related Entamoeba histolytica transformants
DescriptionEntamoeba histolytica, the protozoan parasite responsible for amoebiasis, employs a diverse arsenal of virulence factors to facilitate infection and evade host immune responses. In this study, we identify KERP2 as a dual-function effector involved in both parasite homeostasis and host cell modulation. To investigate its subcellular interactions, E. histolytica trophozoites expressing HA-tagged full-length KERP2 or the truncated variant HA-KERP2(1-184) were fractionated into nuclear and cytosolic components, followed by co-immunoprecipitation analysis.
HostingRepositoryMassIVE
AnnounceDate2026-02-26
AnnouncementXMLSubmission_2026-02-26_07:08:59.698.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterruofan peng
SpeciesList scientific name: Entamoeba histolytica HM-1:IMSS; NCBI TaxID: 294381;
ModificationListPhospho
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-04-03 01:44:20ID requested
12026-02-26 07:09:00announced
Publication List
no publication
Keyword List
submitter keyword: Entamoeba histolytica, virulence factor, fractionation, DatasetType:Proteomics
Contact List
Ruofan Peng
contact affiliationThe University of Tokyo
contact emailruofan@m.u-tokyo.ac.jp
lab head
ruofan peng
contact affiliationUniversity of Tokyo
contact emailprfbcd@gmail.com
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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