PXD062550 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | A proteomic analysis of WASH complex subunit 3 deficiency in adult heart. |
| Description | The WASH complex is primarily responsible for the activation of actin branching on endosomes, regulating vesicle trafficking across intracellular organelles. As one of the core subunits of the WASH complex, the function of washc3 remains largely unknown. In this study, we performed proteomic analysis of washc3 mutant, focusing specifically on the adult heart. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-09 |
| AnnouncementXML | Submission_2026-03-08_18:15:01.215.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Marcin Luzarowski |
| SpeciesList | scientific name: Danio rerio (Zebrafish) (Brachydanio rerio); NCBI TaxID: NEWT:7955; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
| 0 | 2025-04-03 00:37:28 | ID requested | |
| ⏵ 1 | 2026-03-08 18:15:02 | announced | |
Publication List
| Kim S, Park DD, Glazier A, Rottbauer W, Just S, WASHC3 knockout disrupts mitochondrial protein homeostasis and energy metabolism in cardiomyocytes. Front Cardiovasc Med, 13():1682381(2026) [pubmed] |
| 10.3389/fcvm.2026.1682381; |
Keyword List
| submitter keyword: Heart, Mitochondria, WASH3, Zebrafish, Proteomics |
Contact List
| Marcin Luzarowski |
| contact affiliation | Core Facility for Mass Spectrometry and Proteomics, Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, 69120 Heidelberg, Germany |
| contact email | m.luzarowski@zmbh.uni-heidelberg.de |
| lab head | |
| Marcin Luzarowski |
| contact affiliation | University of Heidelberg |
| contact email | m.luzarowski@zmbh.uni-heidelberg.de |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD062550 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD062550
- Label: PRIDE project
- Name: A proteomic analysis of WASH complex subunit 3 deficiency in adult heart.