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PXD062550

PXD062550 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleA proteomic analysis of WASH complex subunit 3 deficiency in adult heart.
DescriptionThe WASH complex is primarily responsible for the activation of actin branching on endosomes, regulating vesicle trafficking across intracellular organelles. As one of the core subunits of the WASH complex, the function of washc3 remains largely unknown. In this study, we performed proteomic analysis of washc3 mutant, focusing specifically on the adult heart.
HostingRepositoryPRIDE
AnnounceDate2026-03-09
AnnouncementXMLSubmission_2026-03-08_18:15:01.215.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMarcin Luzarowski
SpeciesList scientific name: Danio rerio (Zebrafish) (Brachydanio rerio); NCBI TaxID: NEWT:7955;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-04-03 00:37:28ID requested
12026-03-08 18:15:02announced
Publication List
Kim S, Park DD, Glazier A, Rottbauer W, Just S, WASHC3 knockout disrupts mitochondrial protein homeostasis and energy metabolism in cardiomyocytes. Front Cardiovasc Med, 13():1682381(2026) [pubmed]
10.3389/fcvm.2026.1682381;
Keyword List
submitter keyword: Heart, Mitochondria, WASH3, Zebrafish, Proteomics
Contact List
Marcin Luzarowski
contact affiliationCore Facility for Mass Spectrometry and Proteomics, Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, 69120 Heidelberg, Germany
contact emailm.luzarowski@zmbh.uni-heidelberg.de
lab head
Marcin Luzarowski
contact affiliationUniversity of Heidelberg
contact emailm.luzarowski@zmbh.uni-heidelberg.de
dataset submitter
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Dataset FTP location
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PRIDE project URI
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