PXD062452 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Shotgun analysis of proteins in HeLa cells following treatment with polyamine affinity-based probes |
| Description | HeLa cells were incubated with affinity-based probes, synthetic analogs of endogenous metabolites: putrescine, spermidine, and spermine. Cells were photoirradiated briefly and proteins were extracted, digested with trypsin, and the resulting peptides were labeled with TMT. Proteins were quantified across conditions to assess the effect of polyamine analogs on total protein levels in cells. This dataset is related to dataset PXD058706 (HeLa cell protein interactome of polyamine affinity-based probes). |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-09-22 |
| AnnouncementXML | Submission_2025-09-22_05:08:21.168.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Remigiusz Serwa |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-04-01 02:50:05 | ID requested | |
| ⏵ 1 | 2025-09-22 05:08:21 | announced | |
Publication List
Keyword List
| submitter keyword: HeLa, total protein levels,Polyamines, affinity-based probes |
Contact List
| Remigiusz Serwa |
|---|
| contact affiliation | IMol Institute, Polish Academy of Sciences, Warsaw, Poland |
| contact email | r.serwa@imol.edu.pl |
| lab head | |
| Remigiusz Serwa |
|---|
| contact affiliation | The International Institute of Molecular Mechanisms and Machines, Polish Academy of Sciences |
| contact email | r.serwa@imol.edu.pl |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD062452 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD062452
- Label: PRIDE project
- Name: Shotgun analysis of proteins in HeLa cells following treatment with polyamine affinity-based probes
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